She was taking no other medications except for multivitamins. She denied alcohol abuse and risk factors for viral hepatitis. She had no history of liver disease, but had a previous cholecystectomy. Repeated episodes of acute hepatitis after use of Move Free.( 1)Ī 78 year old woman osteoarthritis developed jaundice within 3 weeks of starting “Move Free Advanced”, a proprietary multi-ingredient nutritional supplement advertised to be helpful for joint discomfort. Likelihood score: C (probable rare cause of clinically apparent liver injury).Ĭase 1. At present, Move Free products do not list a proprietary herbal component but do mention a proprietary mineral complex with a similar name: “Uniflex”. While further cases have not been described, prospective studies of drug induced liver injury from the United States mentioned 3 cases of acute liver injury linked to Move Free products, all from 2012-2013. One patient restarted the product after at least partial recovery and redeveloped a similar pattern of liver injury. Immunoallergic and autoimmune features were not present, and the injury resolved without residual in all cases. The injury was moderate in severity and resolved within 1 to 2 months of stopping the supplement. These publications described an acute hepatocellular injury arising within 1 to 3 weeks of starting a Move Free product that contained glucosamine, chondroitin and a proprietary herbal mixture of Chinese skullcap (Scutellaria baicalensis) and black catechu (Acacia catechu). The initial reports of liver injury attributed to Move Free were published in 2010, with subsequent reports in 20, all from the United States. Proprietary Blend (353 mg): Krill oil, Hyaluronic acid, Astaxanthin Proprietary Blend (250 mg): Tamarindus indicus (seed) extract and Curcuma longa (rhizome) extract, microcrystalline celluloseĬartilage Blend (40 mg), Hyaluronic acid (3.3 mg), Boron (5 mg) Glucosamine (1.5 g), Chondroitin (200 mg), Melatonin (6 mg)Ĭalcium (35 mg), Calcium fructoborate (216 mg) Glucosamine (1.5 g), Chondroitin (200 mg), Methylsulfonylmethane (MSM: 750 mg), Vitamin D3 (2000 IU), Hyaluronic acid (3.3 mg), Uniflex” FruiteX-B Calcium Fructoborate (216 mg).
Move free ultra muscle gain plus#
Move Free Joint Health, Advanced Plus MSM & Vitamin D3
Glucosamine (1.5 g), Chondroitin (200 mg), Methylsulfonylmethane (MSM: 1.5 g), Hyaluronic acid (3.3 mg), “Uniflex” FruiteX-B Calcium Fructoborate (216 mg). Move Free Joint Health, Advanced Plus with MSM Glucosamine (1.5 g), Chondroitin (200 mg), Hyaluronic acid (3.3 mg), “Uniflex” FruiteX-B Calcium Fructoborate (216 mg). These multi-ingredient products appear to be generally safe and well tolerated, but prospective studies of their efficacy, tolerance and safety have not been published. Dietary supplements are not recommended for specific medical conditions, but can be advertised as being supportive of general health or a specific tissue or organ health. However, all nutritional supplements are subject to rules regarding purity and good manufacturing practices. Because the products are considered dietary supplements, they are not subject to the usual efficacy and safety evaluation given to medications. The common Move Free products that are currently marketed are given in the Table below with a listing of their ingredients as provided in the product labels. Presently, however, Move Free products do not list any herbal constituents although several mention “Uniflex (FruiteX-B Calcium Fructoborate)”.
Previous Move Free products have included mixtures of herbal agents including Chinese skullcap (Scutellaria baicalensis) and black catechu (Acacia catechu). The ingredients and their concentrations in some of the products have been modified over time. The constituents of the various Move Free products vary, but are largely glucosamine, chondroitin and hyaluronic acid with various combinations of vitamins (vitamin D3), minerals (boron) and selected nutritional supplements such as krill oil and astaxanthin (a keto-carotenoid anti-oxidant). The Move Free brand is currently produced by Reckitt Benckiser Group plc (Slough, England) which purchased its previous distributor, Schiff Nutrition International (Salt Lake City, UT), in 2012. Move Free is a proprietary product name for an array of multi-ingredient herbal and dietary supplements (MIDS) meant to ease joint discomfort.
0 kommentar(er)
